How does Akarkara work?

The antioxidant, anti-inflammatory, and analgesic properties of Akarkara shown in cell culture and animal experiments are likely caused by the various phytochemicals — phenols, flavonoids, tannins, and polysaccharides — identified in Anacyclus pyrethrum extracts.^{[1][2][3][4][5][6][7]} However, determining exactly how extracts from Anacyclus pyrethrum cause the numerous documented benefits in animal experiments will only be possible if mechanistic studies are completed. Therefore, it is currently unclear exactly how Akarkara might protect against seizures,^{[8][6][9][10]} enhance memory,^[10][11] improve sperm health,^[12][7] or increase libido,^[13][14] as shown in animal models. Furthermore, these effects must be tested in clinical trials to demonstrate the relevance of Akarkara supplements to human health.