How does alpha-GPC work?

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    Last Updated: May 16, 2025

    Alpha-GPC works by increasing the synthesis and release of acetylcholine in the brain, which is important for memory, motivation, arousal, and attention. Additionally, higher acetylcholine levels may enhance muscle contraction signals, which could potentially lead to increased force production.

    Mechanistic evidence suggests that alpha-GPC exerts its effects by increasing the synthesis and release of acetylcholine in the brain, where it is involved in memory, motivation, arousal, and attention.[1][2][3][4]

    Acetylcholine is also responsible for the action potentials that stimulate muscles to contract. Therefore, it’s theorized that increased acetylcholine levels lead to a stronger signal for muscle contraction and, consequently, to increased force production.