How does apigenin work?

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    Last Updated: May 16, 2025

    Apigenin may prevent genetic mutations in toxin-exposed cells and contribute to the removal of free radicals, inhibition of tumor growth enzymes, and induction of detoxification enzymes. Its anti-inflammatory properties could also influence mental health and immune responses, although some studies do not support its effects on metabolic conditions.

    Animal studies suggest that apigenin may impede genetic mutations in cells that are exposed to toxins and bacteria.[1][2] Apigenin may also play a direct role in the removal of free radicals, inhibition of tumor growth enzymes, and induction of detoxification enzymes such as glutathione.[3][4][5][6] Apigenin’s anti-inflammatory ability may also explain its effects on mental health, brain function, and immunological response,[7][6][8][9] though some large observational studies don’t support a potential effect with respect to metabolic conditions.[10]