HA is a large hydrophilic molecule. When it is released from cells, it binds water, and this helps with hydration of the cells. It also attracts fluid into the synovial fluid of the joints and the vitreous fluid in the eye, hydrating and lubricating these areas. When it is produced by cells, HA is a long molecule with a high molecular weight. In this form, it binds to certain proteins produced by the immune system, such as IL-8, and prevents autoimmune responses and inflammation.[1]
How does Hyaluronic Acid work?
Written by:
Fact-checked
by:
•Last Updated: May 16, 2025
Hyaluronic acid (HA) binds water, which helps with cell hydration, and attracts fluid to synovial and vitreous fluids to provide lubrication. When produced by cells, HA binds to immune system proteins and prevents autoimmune responses and inflammation.