How does Rhodiola rosea work?

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    Last Updated: May 16, 2025

    Rhodiola rosea alleviates psychological stress and anxiety and may also interact with cellular stress-response signaling, which suggests benefits at both the cellular and systemic levels. Its antistress effects may partly result from its ability to reduce cortisol release during stress.

    Although it is known for its ability to alleviate psychological stress and anxiety, rhodiola has also been shown to interact with cellular stress-response signaling in in vitro studies, indicating that it may have benefits at the cellular level as well as the systemic level. The mechanisms behind rhodiola’s ability to mitigate stress in humans are complex and not well understood. The anti-stress effects of rhodiola may occur in part due to it being able to blunt cortisol release under stressful conditions.[1]