There are no definitive diagnostic tests for CFS, so diagnosis is mainly centered on identifying the characteristic signs and symptoms after ruling out other possible conditions (e.g., hypothyroidism, anemia, lupus erythematosus, cancer).[1]
How is chronic fatigue syndrome diagnosed?
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•Last Updated: May 16, 2025
Chronic fatigue syndrome is diagnosed primarily by identifying its characteristic signs and symptoms because there are no definitive tests for the condition. Diagnosis also involves ruling out other potential conditions such as hypothyroidism, anemia, lupus erythematosus, and cancer.