Because of poor connective tissue integrity, people with EDS are at an increased risk of life-threatening complications, such as vascular and organ rupture, spontaneous pneumothorax (collapsed lung), and excessive bleeding. The risk of life-threatening complications is greatest among people with vascular and kyphoscoliotic EDS. However, people with other subtypes of EDS are still vulnerable to these complications and should take preventative measures, such as receiving regular medical care, monitoring symptoms, and avoiding strenuous contact sports.[1]
Is EDS life-threatening?
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•Last Updated: April 23, 2025
People with Ehlers-Danlos Syndrome (EDS) face an increased risk of life-threatening complications, particularly those with vascular and kyphoscoliotic EDS, due to poor connective tissue integrity. People with all subtypes of EDS should take preventative measures, including regular medical care and symptom monitoring, to mitigate these risks.