Yes, if an individual is experiencing mild soreness and can move comfortably, exercising is safe. In cases where the individual is experiencing debilitating soreness, extreme weakness, and fatigue, it is best to wait until the symptoms subside, as exercising in this state can increase the risk of injury.[1] There is also some evidence that exercise may alleviate DOMS pain, but this relief is typically short-lived, and the discomfort will return after the exercise is finished.[2]