Some dietary supplements and treatments show a mild to moderate effect in preventing DOMS. Unfortunately, there is no guaranteed way to prevent DOMS. The best bet for preventing and/or reducing DOMS is to gradually increase exercise intensity while adhering to fundamental recovery principles (e.g., optimal sleep, adequate hydration, and proper nutrition).[1]
Performing the same exercise routine in subsequent workouts can reduce soreness, a phenomenon known as the repeated bout effect. Repeated exposure to the exercise or movement triggers physiological adaptations that result in less muscle damage and soreness in future workouts.[2]