Aloe vera is commercially sold to treat burns and various skin conditions. While the evidence supporting its effectiveness is not robust, one meta-analysis suggested that burns treated with Aloe vera may heal more quickly than those given standard treatment.[1] Similarly, some studies indicate that Aloe vera may reduce the severity of psoriasis symptoms in individuals with mucocutaneous conditions.[2] However, Aloe vera does not seem to be effective in improving symptoms of radiation dermatitis (RD), a common side effect of radiotherapy.[3]
Topical application of Aloe vera may also be beneficial for nipple pain and irritation in breastfeeding women,[4] although further research with stronger methodologies is needed to confirm these findings.
Additionally, Aloe vera may have benefits for oral health. Topical oral applications of Aloe vera in mouthwash or gels have been shown to reduce plaque formation, gum inflammation, and bleeding in people with periodontal disease (gum disease) to a greater degree than commonly used preparations (e.g., fluoride‑containing triclosan, chlorhexidine).[5] Furthermore, one meta-analysis found that, for the treatment of oral ulcers, various topical preparations of Aloe vera gel had better therapeutic effect and shorter therapy duration than a control, although their effects on ulcer size and subjective pain did not differ significantly from the control.[6]
Finally, some Aloe vera preparations can also be taken orally, and one meta-analysis found that Aloe vera may be effective in improving symptoms of irritable bowel syndrome (IBS), although the evidence is not strong.[7]