There is interest in using bitter orange for weight loss and improvement in body composition (fat loss). However, this is not supported by clinical data.[1] Bitter orange is also used for athletic performance, but its benefit is not clear.[2]
One study found that applying bitter orange oil 20–25% to affected skin for 1 to 3 weeks was associated with cure of fungal infections like ringworm, jock itch, or athlete’s foot.[3] However, that study was limited by a lack of control group.