What are CBD’s main drawbacks?

    Last Updated: May 16, 2025

    CBD's main drawbacks include minor adverse effects such as lethargy, fatigue, and gastrointestinal issues, as well as a lack of substantial human evidence, unreliable product quality, and ambiguous legal status.

    CBD’s adverse effects are usually minor, but they include lethargy, fatigue, sleepiness, fever, diarrhea, vomiting, decreased appetite, and increased levels of alanine aminotransferase (a marker of liver damage).[1][2][3]

    Other drawbacks include a paucity of human evidence, the unreliability of most CBD products on the market, and the “gray area” legality of CBD products.

    What are CBD’s main drawbacks? - Examine