Although DHEA supplementation increases androgens, these small increases may only prompt zero-to-small changes to muscle size and strength: a 2018 systematic review of randomized controlled trials (RCTs) concluded that supplementation with DHEA had no effects on muscle size or strength,[1] and a 2020 meta-analysis of RCTs found small benefits (often at doses 50–100 mg) to body composition: increased lean body mass (0.99 lbs) and decreased fat mass (-1%).[2]