What are Fadogia agrestis’ main drawbacks?

    Last Updated: May 16, 2025

    Fadogia agrestis may increase testosterone levels based on a rodent study, but more extensive research is needed to confirm this effect and investigate potential cytotoxicity that could arise after prolonged use. Additionally, the lack of human trials raises concerns about its safety for consumption.

    Although one rodent study noted fairly remarkable increases in testosterone over the course of five days with the use of Fadogia agrestis,[1] more and lengthier studies are required to investigate this effect, as there is also a possible cytotoxic effect that can manifest after around a month, which could interfere with the testosterone-boosting properties of the plant.[2] It’s worth noting that the potential cytotoxic effects of Fadogia agrestis may not be limited to the testicles, with more studies required to determine what exactly is occurring.