Fluoride’s claim to fame is its ability to stop and reverse tooth decay: when topically applied to the teeth (e.g., in toothpaste or water), it’s integrated into the structure of the enamel. It simultaneously inhibits demineralization and promotes remineralization of the tooth, as well as blocking the activity of plaque-forming bacteria.[1] Toothpaste containing 1000 to 1250 ppm of fluoride prevents caries to a greater degree than non-fluoride toothpaste.[2] Fluoride also plays a role in bone formation and has been used for preventing osteoporosis.[3]
What are fluoride’s main benefits?
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•Last Updated: May 16, 2025
Fluoride is primarily known for its ability to stop and reverse tooth decay by integrating into the tooth enamel, inhibiting demineralization, promoting remineralization, and blocking plaque-forming bacteria. Additionally, it contributes to bone formation and has been used to prevent osteoporosis.