What are GlyNAC’s main drawbacks?

    Written by:
    Nick Milazzo, Giulia Guerrini

    Fact-checked

    by:

    Katie Jantz
    Last Updated: May 16, 2025

    GlyNAC has no notable side effects reported in the literature, but there are instances in which N-acetylcysteine (NAC) can cause nausea, vomiting, and diarrhea. Additionally, intravenous administration of NAC or GlyNAC carries a risk of overdose, which can lead to severe complications such as hemolysis, thrombocytopenia, kidney failure, and potentially death.

    No notable side effects have been reported in the GlyNAC literature, although there have been some documented instances of NAC causing nausea, vomiting, and diarrhea.[1][2]

    When NAC or GlyNAC are taken intravenously, NAC overdose is possible, and can result in red blood cell breakdown (hemolysis), low blood platelet count (thrombocytopenia), kidney failure, and possibly death.[3]