HA is useful in several branches of medicine. Ophthalmologists use it in the treatment of dry eye syndrome,[1] orthopedics specialists use it for different types of arthritis and joint pain,[2][3][4] and aesthetic practitioners use HA in fillers.[5] It seems to have potential in other areas, too, such as wound healing and the treatment of burns.[6][7] In all of these applications, HA helps with hydration, lubrication, and tissue regeneration. High-molecular-weight HA is produced in healthy cells. Molecular weight is measured in daltons, which is the unit used to express the weight of atoms and larger molecules. A high molecular weight for HA is above 2000 kilodaltons (kDa). High-molecular-weight HA is associated with anti-inflammatory effects, and seems to slow down immune responses.[8] Other potential uses that are being looked into include alopecia treatments, regeneration of nerves in peripheral neuropathy, and use of HA in vascular grafts to help with healing.[9][10]
What are hyaluronic acid’s main benefits?
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•Last Updated: May 16, 2025
Hyaluronic acid (HA) is beneficial in various conditions, including dry eye disease, arthritis, and joint pain, and it also shows potential in wound healing and burns. It aids in hydration, lubrication, and tissue regeneration, and high-molecular-weight HA offers anti-inflammatory effects and potential applications in alopecia, nerve regeneration, and vascular graft healing.