What are lemon balm’s main drawbacks?

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    Last Updated: May 16, 2025

    Lemon balm has a strong safety record and no reports of serious negative effects, but it may reduce alertness, which poses risks for activities like driving. Additionally, caution is advised for people with glaucoma, people with thyroid conditions, or people who are taking selective serotonin reuptake inhibitors (SSRIs) because lemon balm could potentially affect intraocular pressure, thyroid hormone levels, or medication effectiveness.

    As might be expected given its 2,000-year history of traditional use as a food, tea and medicine, lemon balm has an excellent safety track record. No serious negative effects have been associated with lemon balm to date.[1] The flip side of lemon balm’s calming, sedative effect, however, is that it may reduce alertness.[2][3][1]

    Other things to be aware of:

    • People with glaucoma should use care because of anecdotal reports that lemon balm may increase intraocular pressure.[2][1]
    • People with thyroid conditions should use care because of the theoretical possibility of lemon balm affecting thyroid hormone levels.[4][5][6][7][8]
    • People who take selective serotonin reuptake inhibitors (SSRIs) should be aware of the theoretical possibility that lemon balm could reduce their effectiveness.[3][1]