MSM is primarily used in osteoarthritis. While studies show it can improve pain and function in people with osteoarthritis of the knee, the benefits are small and often clinically insignificant.[1][2][3][4][5] Taking MSM might also benefit osteoarthritis in other joints, including the lumbar spine, the ankle, and the shoulder. It might also improve joint pain in people who do not have arthritis. However, the evidence is not conclusive, and more well-designed controlled trials are needed to confirm these findings.[6][7][8]
What are MSM’s main benefits?
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•Last Updated: October 29, 2024