Overall, the results of randomized controlled trials of phosphatidylserine (PS) have been inconsistent. Trials examining PS for cognition in adults over age 50 have somewhat consistently showed benefits at dosages of 100–300 mg per day for 2–6 months, although more research is needed to clarify these benefits.[1][2][3][4] PS supplementation also might reduce perceived stress levels in people with high chronic stress, though studies of PS for stress have serious limitations and have shown mixed results.[5][6][7] PS has also been studied in the context of physical activity, though studies have shown even less consistent results here.[8][9][10][11][12]