What are some of the main medical treatments for diabetic neuropathy?

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    Last Updated: May 16, 2025

    The main medical treatments for diabetic neuropathy focus on improving blood glucose control through lifestyle changes and glucose-lowering medications because there are no specific treatments for nerve damage. Additionally, pain-reducing medications like pregabalin or duloxetine are used to alleviate pain and enhance quality of life, which can also encourage increased physical activity.

    There are no specific treatments for nerve damage, but lowering hyperglycemia (persistently high blood glucose concentrations) reduces the risk of diabetic neuropathy.[1][2][3] Therefore, the main treatment is to improve blood glucose control using lifestyle behavior change (diet, exercise, and weight management counseling) and glucose-lowering drugs.[4][5] 

    Since diabetic neuropathies can impair sensation, healthcare providers regularly examine patients’ feet for signs of damage to help prevent diabetic foot ulcers. To treat pain associated with diabetic neuropathies, pain-reducing medications (e.g., pregabalin or duloxetine) are used to improve quality of life.[6][7] Reducing pain also helps patients increase their levels of daily physical activity, which improves blood glucose control.[8]

    What are some of the main medical treatments for diabetic neuropathy? - Examine