The use of topical barrier creams and topical corticosteroids, such as hydrocortisone, are typically the first line of treatment. Oral and topical antihistamines are also commonly used early. If this proves insufficient, immunosuppressive (focused on curtailing the excessive immune system activation) drugs are frequently employed. Some such drugs and drug types include monoclonal antibodies, JAK inhibitors, steroids, calcineurin inhibitors, methotrexate, mycophenolate mofetil, and cromoglycate. Phosphodiesterase inhibitors are also sometimes used to induce vasodilation.
What are some of the main medical treatments for eczema?
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•Last Updated: May 16, 2025
The main medical treatments for eczema include topical barrier creams and corticosteroids as first-line options, along with oral and topical antihistamines. If these are insufficient, immunosuppressive drugs such as monoclonal antibodies, JAK inhibitors, and others may be used.