Over-the-counter Nonsteroidal anti-inflammatory drugs (NSAIDs) are the go-to treatment for menstrual cramps as they lower prostaglandin production and thus reduce cramping.[1] Check with your healthcare provider before taking NSAIDs.
For patients with significant primary dysmenorrhea (cramps not caused by another disease process), occasionally oral contraceptive pills may be recommended by a doctor as they may reduce episodes of cramping as well.
Seek medical help if menstrual pain is not relieved by NSAIDs or other self-care practices, cramps happen when you are or may be pregnant, cramps suddenly become worse, you are over 25 years of age and get severe cramps for the first time, cramps are accompanied by a fever, or you experience pain not around the time of menstruation.[2]