A drug called rivastigmine, a cholinesterase inhibitor, is used to treat dementia in people with Parkinson's disease (or Alzheimer's).[1] Other treatments for non-motor symptoms are similar to treatments used for the same symptoms in people without Parkinson's disease.[2] For example, selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, and norepinephrine reuptake inhibitors are used to treat depression in people with Parkinson's disease.[2] Melatonin has shown some efficacy for treating daytime fatigue and excessive daytime sleepiness in people with Parkinson's disease through improving sleep quality.[3] Although modafinil is often prescribed for excessive daytime sleepiness, it failed to improve objective measures of sleepiness in people with Parkinson's disease in a randomized controlled trial.[4]
What are some of the main medical treatments for non-motor symptoms of Parkinson’s?
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•Last Updated: October 13, 2024