Because Parkinson’s reduces dopamine levels in the brain through the death of dopamine-generating neurons, the main medical treatment strategies are centered on dopamine.[1] A few of the most common dopamine-based treatments are levodopa, which nerve cells use as a precursor to make dopamine; monoamine oxidase-B (MAO-B) inhibitors, which increase dopamine levels by reducing its breakdown; and dopamine agonists, which mimic the effects of dopamine.[2] Anticholinergic drugs are also used to help reduce tremors and muscle stiffness, and amantadine may be prescribed to suppress involuntary movements.[2]
What are some of the main medical treatments for Parkinson’s disease?
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•Last Updated: May 16, 2025
The main medical treatments for Parkinson's disease focus on increasing dopamine levels, and common options include levodopa, MAO-B inhibitors, and dopamine agonists. Additionally, anticholinergic drugs can help reduce tremors and muscle stiffness, and amantadine may be used to suppress involuntary movements.