Different types of EDS present with different signs and symptoms. People with hypermobile EDS (hEDS) often present with overly flexible and unstable joints, overly stretchy and thin skin, and excessive bruising. EDS can cause a number of secondary complications, such as chronic pain (due to damage to unstable joints), dysautonomia, gastrointestinal dysmotility, mast cell activation (allergies, asthma, etc), and anxiety and phobias. Serious complications, such as vascular or organ rupture, have been reported in vascular and kyphoscoliotic EDS, but all types of EDS should be regularly monitored for serious complications.[1]
What are the main signs and symptoms of Ehlers-Danlos syndrome (EDS)?
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•Last Updated: May 16, 2025
Ehlers-Danlos syndrome (EDS) has various signs and symptoms depending on the type; hypermobile EDS (hEDS) is characterized by overly flexible joints, stretchy skin, and excessive bruising. It can lead to secondary complications like chronic pain, dysautonomia, and anxiety, and serious complications may occur in vascular and kyphoscoliotic EDS, necessitating regular monitoring.