What are the other benefits of glucosamine?

There is evidence to suggest that glucosamine supplementation may have beneficial effects on mobility and pain reduction in people with Kashin-Beck disease (KBD), a degenerative bone disease characterized by cartilage degradation, similar to osteoarthritis. In one double-blind study, it was observed that individuals with KBD who took 750 mg of glucosamine sulfate twice daily (a total of 1500 mg daily) for 6 weeks experienced reduced pain and improved physical functionality. Interestingly, the effects of glucosamine were comparable to those of the anti-inflammatory medications used in the control groups, which included diclofenac sodium (50 mg twice a day) and naproxen (300 mg twice a day).^[1]