Gout is the result of MSU crystals forming in joints. The primary cause of MSU crystal formation is high levels of uric acid in the blood, either from a reduced ability to excrete uric acid or an increased production of uric acid. A variety of factors have been linked to a higher risk of gout, including heavy drinking, obesity, various dietary factors, certain medications, and kidney disease. Genetics can also contribute to higher uric acid levels and an increased risk of gout.
What causes gout?
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•Last Updated: May 16, 2025
Gout occurs when monosodium urate crystals form in the joints and typically results from elevated uric acid levels in the blood. Risk factors include excessive alcohol consumption, obesity, certain dietary habits, specific medications, kidney disease, and genetic predisposition.