What causes intestinal candidiasis?

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    Last Updated: May 16, 2025

    The risk of intestinal candidiasis is higher in preterm infants, critically ill or immunocompromised individuals, people with diabetes, and in people who are taking certain medications, like antibiotics, antifungals, and steroids. Additionally, oral candidiasis can increase intestinal Candida counts.

    Most cases of IC (and subsequent invasive infection) are seen in preterm infants and critically ill or immunocompromised individuals. Additionally, certain medications, such as antibiotics and steroids, permeable intestines, invasive surgical procedures, hospitalization, and the use of broad-spectrum antibiotics make premature infants more prone to IC and invasive infections.[1]

    People with diabetes may also be more prone to IC, but these findings are complicated by this population’s comparatively high use of antifungals, antibiotics, and steroids (to control inflammation). Intestinal Candida counts can also be elevated as a result of swallowing oral Candida, and oral candidiasis (overgrowth of yeast in the mouth and throat) can occur in people who wear dentures or take the aforementioned medications.[2][3][4]