Intestinal hypermotility (increased contractions of the intestines), from a developmental dysregulation of the nervous system, may contribute to colic.[1][2][3] Imbalances of the parasympathetic and sympathetic nervous systems (which balance resting/digesting, and fight/flight responses, respectively) have been investigated but do not appear to be a cause of infantile colic.[4]
What developmental causes could contribute to infantile colic?
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•Last Updated: May 16, 2025
Intestinal hypermotility, which results from a developmental dysregulation of the nervous system, may contribute to infantile colic, whereas imbalances in the parasympathetic and sympathetic nervous systems do not seem to be a cause of the condition.