AAMCD is a term used to describe the decline in cognitive function that accompanies normal aging. It is different from pathologic types of cognitive decline – such as Alzheimer’s disease – in that it does not reduce quality of life.
What is age-associated memory impairment & cognitive decline?
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•Last Updated: May 16, 2025
Age-associated memory impairment and cognitive decline (AAMCD) refers to the natural decline in cognitive function that occurs with aging. Unlike pathological cognitive decline, such as Alzheimer's disease, AAMCD does not negatively affect quality of life.