Alpha-GPC (alpha-glycerophosphocholine or choline alphoscerate) is a choline-containing phospholipid. When ingested, alpha-GPC is rapidly absorbed and easily crosses the blood-brain barrier. It is metabolized into choline and glycerol-1-phosphate. Choline is a precursor of acetylcholine, a neurotransmitter involved in memory, attention, and skeletal muscle contraction. Glycerol-1-phosphate is used to support cellular membranes.[1]
What is alpha-GPC?
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•Last Updated: May 16, 2025
Alpha-GPC is a choline-containing phospholipid that is quickly absorbed and crosses the blood-brain barrier, where it is metabolized into choline and glycerol-1-phosphate. Choline serves as a precursor for acetylcholine, a neurotransmitter important for memory, attention, and muscle contraction.