What is GABA?

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    Last Updated: October 13, 2024

    GABA is the major inhibitory neurotransmitter in the central nervous system. It fulfills a number of functions in the brain and affects nonneuronal tissues outside the brain. GABA regulates many depressive and sedative actions and is critical for relaxation.[1][2][3][4] Consequently, several drugs that resemble the structure of GABA (e.g., baclofen, gabapentin, and pregabalin) have been developed to treat seizures and convulsions. GABA is also involved in the neural regulation of visual tasks and emotion processing.[5]