What is hesperidin?

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    Last Updated: May 16, 2025

    Hesperidin is a flavanone glycoside found in the spongy inner peel of citrus fruits and is derived from the term "hesperidium." Its aglycone form is known as hesperetin.

    Hesperidin is a flavanone glycoside (a type of flavonoid) that was isolated from the spongy inner peel of oranges, which is known as the mesocarp.[1]

    Hesperidin (Hsd) is prominently found in citrus fruits like oranges, lemons, clementines, mandarins, and grapefruits. The name hesperidin is derived from the word “hesperidium”, a word for a berry with a pulpy, segmented interior and a leathery rind containing aromatic oils.[2][3] Its aglycone (i.e., missing a glycosyl group) form is called hesperetin (Hst).[4]

    What is hesperidin? - Examine