MSM is an organosulfur compound that occurs naturally in some plants and animals. MSM is a product of the sulfur cycle — a cycle through which sulfur moves between the air, ground, and living things. Through this process MSM is eventually absorbed into the soil, where it can be taken up by plants and therefore is found in fruit, vegetables, and grains. MSM can also be manufactured by oxidizing another organosulfur compound, dimethyl sulfoxide (DMSO). There is no difference structurally between manufactured and naturally-occurring MSM, and the manufactured products are equally safe and make it much easier to reach the recommended dose.[1]