What is rheumatoid arthritis?

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    Last Updated: May 16, 2025

    Rheumatoid arthritis (RA) is an autoimmune condition that causes inflammation of the joints when the immune system attacks protective tissue, which leads to pain, swelling, and potential joint destruction. Unlike osteoarthritis, RA results in a distinct type of "squishy" joint swelling rather than the hard, bony enlargements that are typical of osteoarthritis.

    Arthritis means inflammation of the joints. Unlike osteoarthritis (OA), the most common form of arthritis that is caused by general wear and tear, RA is caused by an autoimmune reaction where the immune system attacks the tissue that protects joints, leading to the characteristic pain, swelling, inflammation and eventual joint destruction. RA tends to affect the joints in a different way than OA. RA joints have a distinct, more 'squishy' type of joint swelling in contrast to the type of hard, bony enlargement of joints that is often seen in the fingers of people with OA.