Will supplementing melatonin affect my own production of melatonin?

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    Last Updated: October 13, 2024

    Supplementing melatonin doesn’t appear to affect the body’s own production in a negative way. Studies that have administered melatonin at doses of 0.5 mg,[1] 5.0 mg,[2] and 50 mg[1] have found no significant effect on the body's ability to produce a basal level of melatonin. One trial even found that people with insomnia who took 2 mg of melatonin nightly for 6 months had higher natural melatonin synthesis after cessation of the supplement than a historical sample of participants with insomnia who didn't take melatonin.[3]