Do artificially sweetened beverages cause insulin spikes?

ASBs, and NNS in general, do not cause insulin to increase in the bloodstream. Hypotheses suggesting that ASBs and NNS could initiate an insulin response, by either a central or a hormonal mechanism, have not been supported by research. Multiple studies have been done showing that artificial sweeteners do not impact blood sugar or insulin levels, whether taken alone or with a meal.^{[1][2][3][1][4]}