In oral mucositis, many studies used a dose of 20 mL (approximately 1 tablespoon) of honey swallowed before and after radiation therapy.^[1]

For cough in children, doses of 5–10 mL (approximately 1–2 teaspoons), for example, in 90 mL of milk, have been studied.^[2]

For skin, a majority of studies applied honey topically to the affected areas.^[3][4][5]

A 2023 meta-analysis of 18 RCTs which examined honey for metabolic health did not find a dose-response effect for any outcomes, except the improvements of systolic blood pressure were not as large when the dose was over 10% of daily total calories (50–62 grams for people eating 2,000–2,500 calories per day). In other words, higher dosages did not increase or decrease the effectiveness of honey for improving metabolic outcomes in some studies. The researchers in this meta-analysis did note that they examined studies which used honey at doses of 5–125 grams, with a median dose of 40 grams (approximately 3 tablespoons).^[6]