Examine Database: Headaches
| Intervention | Grade | Effect | Detail |
|---|---|---|---|
| Caffeine | B | ||
| Bitter orange | D | ||
| Peppermint | B | ||
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| Lactase Enzyme | |||
| Kefir | |||
| Theanine | |||
| Creatine | |||
| Biofeedback | |||
Research FeedRead all studies
Does biofeedback reduce migraine headache frequency?
In this meta-analysis of 9 randomized controlled trials, biofeedback interventions reduced headache frequency in participants with migraines.
Drink more water for better health?
Prebiotic inulin reduces the frequency and severity of migraine headaches
Acetaminophen and caffeine reduce headaches after cesarean delivery with spinal anesthesia
Selenium supplementation, oxidative stress, and migraine severity
Examine Database References
- Lactase Enzyme - Rosado JL, Solomons NW, Lisker R, Bourges HEnzyme replacement therapy for primary adult lactase deficiency. Effective reduction of lactose malabsorption and milk intolerance by direct addition of beta-galactosidase to milk at mealtimeGastroenterology.(1984 Nov)
- Peppermint - Göbel H, Fresenius J, Heinze A, Dworschak M, Soyka DEffectiveness of Oleum menthae piperitae and paracetamol in therapy of headache of the tension typeNervenarzt.(1996 Aug)
- Peppermint - Göbel H, Schmidt G, Soyka DEffect of peppermint and eucalyptus oil preparations on neurophysiological and experimental algesimetric headache parametersCephalalgia.(1994 Jun)
- Kefir - Onder Bekar, Yusuf Yilmaz, Macit GultenKefir improves the efficacy and tolerability of triple therapy in eradicating Helicobacter pyloriJ Med Food.(2011 Apr)
- Theanine - Crystal F Haskell, David O Kennedy, Anthea L Milne, Keith A Wesnes, Andrew B ScholeyThe effects of L-theanine, caffeine and their combination on cognition and moodBiol Psychol.(2008 Feb)
- Lactase Enzyme - Cheng AH, Brunser O, Espinoza J, Fones HL, Monckeberg F, Chichester CO, Rand G, Hourigan AGLong-term acceptance of low-lactose milkAm J Clin Nutr.(1979 Oct)
- Creatine - George Sakellaris, George Nasis, Maria Kotsiou, Maria Tamiolaki, Giorgos Charissis, Athanasios EvangeliouPrevention of traumatic headache, dizziness and fatigue with creatine administration. A pilot studyActa Paediatr.(2008 Jan)
- Bitter orange - Gutiérrez-Hellín J, Salinero JJ, Abían-Vicen J, Areces F, Lara B, Gallo C, Puente C, Del Coso JAcute consumption of p-synephrine does not enhance performance in sprint athletes.Appl Physiol Nutr Metab.(2016-Jan)
- Bitter orange - Min B, Cios D, Kluger J, White CMAbsence of QTc-interval-prolonging or hemodynamic effects of a single dose of bitter-orange extract in healthy subjectsPharmacotherapy.(2005 Dec)
- Bitter orange - Stohs SJ, Preuss HG, Keith SC, Keith PL, Miller H, Kaats GREffects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changesInt J Med Sci.(2011 Apr 28)
- Caffeine - Christopher J Derry, Sheena Derry, R Andrew MooreCaffeine as an analgesic adjuvant for acute pain in adultsCochrane Database Syst Rev.(2014 Dec 11)
- Caffeine - Hadavi SMR, Panah A, Shamohammadi S, Kanaani Nejad F, Sahmeddini MA, Asmarian NThe Prophylactic Effect of Acetaminophen and Caffeine on Post Dural Puncture Headache after Spinal Anesthesia for Cesarean Section: A Randomized Double-Blind Clinical Trial.Iran J Med Sci.(2024 Sep)
- Biofeedback - Paudel P, Sah AEfficacy of biofeedback for migraine: A systematic review and meta-analysis.Complement Ther Med.(2025 Jun)