Mood

    Last Updated: October 13, 2024

    These are supplements which may affect anxiety, depression, and their subclinical and related conditions.

    1,791 participants in 11 trials

    Summary

    These are supplements which may have effects on various mood states and their related consequences. These states include:

    Depression: These are areas that relate directly to how positive or negative people are feeling, including happiness, pleasure, clinical depression, bipolar disorder, etc.

    Anxiety: these are areas that relate directly to nervousness and fear, including common stress, generalized anxiety disorder, and specific anxiety disorders such as obsessive-compulsive disorder.

    Supplements that affect these areas may do so through directly or indirectly affecting the activity and signalling of neurotransmitters, hormones and other signaling molecules, altering brain energetics, neurogenesis, synaptic plasticity, and more. They may do so through being neurotransmitters and hormones, affecting their synthesis, reuptake, and signaling, affecting inflammatory signalling, ion channel function, protecting neurons, and more.

    These categories are highly related to other categories such as Sleep, Energy and Stimulation, and Cognitive Function and Brain Health, both as causes and consequences.

    Examine Database: Mood

    Research FeedRead all studies

    Examine Database References

    1. Cannabis - Timo Woelfl, Cathrin Rohleder, Juliane K Mueller, Bettina Lange, Anne Reuter, Anna Maria Schmidt, Dagmar Koethe, Martin Hellmich, F Markus LewekeEffects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Emotion, Cognition, and Attention: A Double-Blind, Placebo-Controlled, Randomized Experimental Trial in Healthy VolunteersFront Psychiatry.(2020 Nov 13)
    2. Kefir - Z Jenko Pražnikar, S Kenig, T Vardjan, M Černelič Bizjak, A PetelinEffects of kefir or milk supplementation on zonulin in overweight subjectsJ Dairy Sci.(2020 May)
    3. Cannabis - Justin Matheson, Robert E Mann, Beth Sproule, Marilyn A Huestis, Christine M Wickens, Gina Stoduto, Tony P George, Jürgen Rehm, Bernard Le Foll, Bruna BrandsAcute and residual mood and cognitive performance of young adults following smoked cannabisPharmacol Biochem Behav.(2020 Jul)
    4. Cannabis - Anthony N Nicholson, Claire Turner, Barbara M Stone, Philip J RobsonEffect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adultsJ Clin Psychopharmacol.(2004 Jun)
    5. Saffron - Graham Kell, Amanda Rao, Gavin Beccaria, Paul Clayton, Antonio Manuel Inarejos-García, Marin Prodanovaffron ® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trialComplement Ther Med.(2017 Aug)
    6. Cannabis - Alessio Gambino, Marco Cabras, Evangelos Panagiotakos, Federico Calvo, Alessandra Macciotta, Adriana Cafaro, Marco Suria, Giorgia El Haddad, Roberto Broccoletti, Paolo Giacomo ArduinoEvaluating the Suitability and Potential Efficiency of Cannabis sativa Oil for Patients with Primary Burning Mouth Syndrome: A Prospective, Open-Label, Single-Arm Pilot StudyPain Med.(2020 Oct 30)
    7. Tongkat Ali - George A, Suzuki N, Abas AB, Mohri K, Utsuyama M, Hirokawa K, Takara TImmunomodulation in Middle-Aged Humans Via the Ingestion of Physta® Standardized Root Water Extract of Eurycoma longifolia Jack--A Randomized, Double-Blind, Placebo-Controlled, Parallel Study.Phytother Res.(2016-Apr)
    8. Panax Ginseng (Korean Ginseng) - Ellis JM, Reddy PEffects of Panax ginseng on quality of lifeAnn Pharmacother.(2002 Mar)
    9. DHEA - Amanatkar HR, Chibnall JT, Seo BW, Manepalli JN, Grossberg GTImpact of exogenous testosterone on mood: a systematic review and meta-analysis of randomized placebo-controlled trials.Ann Clin Psychiatry.(2014-Feb)
    10. Resveratrol - Marx W, Kelly JT, Marshall S, Cutajar J, Annois B, Pipingas A, Tierney A, Itsiopoulos CEffect of resveratrol supplementation on cognitive performance and mood in adults: a systematic literature review and meta-analysis of randomized controlled trials.Nutr Rev.(2018-Jun-01)
    11. Theanine - Moulin M, Crowley DC, Xiong L, Guthrie N, Lewis EDSafety and Efficacy of AlphaWave(®) L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.Neurol Ther.(2024 Aug)