sVCAM-1

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•Last Updated: October 13, 2024

Soluble vascular cell adhesion molecule-1 (sVCAM-1) is a biomarker for dysfunction in the endothelium, the thin layer of cells lining the heart and blood vessels. Elevated sVCAM-1 is associated with cardiovascular conditions such as hypertension and atherosclerosis.

5,115 participants in 3 trials

Examine Evidence Grades

:

Last Updated:October 13, 2024

5,115 participants in 3 trials

Examine Evidence Grades

Examine Database: sVCAM-1

Alpha-Linolenic Acid (ALA)

D

Participants: 416

No effect

C

Participants: 16

Small Decrease

D

Participants: 2520

No effect

Intervention	Grade	Effect	Detail
Alpha-Linolenic Acid (ALA)	D
Spirulina	C
Flaxseed	D

Examine Database References

Spirulina - Jesús Martínez-Sámano, Adriana Torres-Montes de Oca, Oscar Ivan Luqueño-Bocardo, Patricia V Torres-Durán, Marco A Juárez-OropezaSpirulina maxima Decreases Endothelial Damage and Oxidative Stress Indicators in Patients with Systemic Arterial Hypertension: Results from Exploratory Controlled Clinical TrialMar Drugs.(2018 Dec 8)
Alpha-Linolenic Acid (ALA) - Su H, Liu R, Chang M, Huang J, Jin Q, Wang XEffect of dietary alpha-linolenic acid on blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials.Eur J Nutr.(2018-Apr)
Flaxseed - Askarpour M, Karimi M, Hadi A, Ghaedi E, Symonds ME, Miraghajani M, Javadian PEffect of flaxseed supplementation on markers of inflammation and endothelial function: A systematic review and meta-analysis.Cytokine.(2020 Feb)