Short-chain fatty acid (SCFA)

    Last Updated: October 13, 2024

    SCFAs are fatty acids with fewer than six carbon atoms. They are derived from the fermentation of indigestible foods by the gut microbiota. Certain SCFAs may help regulate appetite, maintain glucose homeostasis, and protect the intestinal epithelial barrier.

    312 participants in 5 trials

    Examine Database: Short-chain fatty acid (SCFA)

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    Examine Database References

    1. Low-FODMAP Diet - Selina R Cox, James O Lindsay, Sébastien Fromentin, Andrew J Stagg, Neil E McCarthy, Nathalie Galleron, Samar B Ibraim, Hugo Roume, Florence Levenez, Nicolas Pons, Nicolas Maziers, Miranda C Lomer, S Dusko Ehrlich, Peter M Irving, Kevin WhelanEffects of Low FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized TrialGastroenterology.(2020 Jan)
    2. Low-FODMAP Diet - Tim J Sloan, Jonna Jalanka, Giles A D Major, Shanthi Krishnasamy, Sue Pritchard, Salah Abdelrazig, Katri Korpela, Gulzar Singh, Claire Mulvenna, Caroline L Hoad, Luca Marciani, David A Barrett, Miranda C E Lomer, Willem M de Vos, Penny A Gowland, Robin C SpillerA low FODMAP diet is associated with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjectsPLoS One.(2018 Jul 26)
    3. Low-FODMAP Diet - Emma P Halmos, Claus T Christophersen, Anthony R Bird, Susan J Shepherd, Peter R Gibson, Jane G MuirDiets that differ in their FODMAP content alter the colonic luminal microenvironmentGut.(2015 Jan)
    4. Low-FODMAP Diet - Bridgette Wilson, Megan Rossi, Tokuwa Kanno, Gareth C Parkes, Simon Anderson, A James Mason, Peter M Irving, Miranda C Lomer, Kevin Whelanβ-Galactooligosaccharide in Conjunction With Low FODMAP Diet Improves Irritable Bowel Syndrome Symptoms but Reduces Fecal BifidobacteriaAm J Gastroenterol.(2020 Jun)
    5. Low-FODMAP Diet - Yawen Zhang, Lijun Feng, Xin Wang, Mark Fox, Liang Luo, Lijun Du, Binrui Chen, Xiaoli Chen, Huiqin He, Shuwen Zhu, Zhefang Hu, Shujie Chen, Yanqin Long, Yubin Zhu, Li Xu, Yanyong Deng, Benjamin Misselwitz, Brian M Lang, Bahtiyar Yilmaz, John J Kim, Chung Owyang, Ning DaiLow fermentable oligosaccharides, disaccharides, monosaccharides, and polyols diet compared with traditional dietary advice for diarrhea-predominant irritable bowel syndrome: a parallel-group, randomized controlled trial with analysis of clinical and microbiological factors associated with patient outcomesAm J Clin Nutr.(2021 Jun 1)