Evidence-based

Serum Bicarbonate

•Last Updated: October 13, 2024

Serum bicarbonate is a way to indirectly measure the pH of the blood, as a higher bicarbonate concentration tends to reflect a more alkaline (buffered) pH. Bicarbonate is reliably increased in oral sodium bicarbonate.

Last Updated:October 13, 2024

Research Snapshot

2,097 participants in 50 trials

Examine Evidence Grades

C2 outcomes

Examine Database: Serum Bicarbonate

Intervention	Grade	Evidence	Effect
Sodium Bicarbonate	C	Participants: 1380	Large Increase
Astaxanthin	C	Participants: 61	Small Decrease
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Sodium Bicarbonate

Large Increase

Astaxanthin

Small Decrease

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Serum Bicarbonate

Examine Database: Serum Bicarbonate

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