Evidence-based

Skeletal Muscle Atrophy

•Last Updated: October 13, 2024

Skeletal muscle atrophy (catabolism) is the loss of lean muscle tissue over time or during inactivity. Compounds that increase atrophy can accelerate this loss while compounds that reduce atrophy are known as 'anti-catabolic'.

Last Updated:October 13, 2024

Research Snapshot

105 participants in 4 trials

Examine Evidence Grades

C2 outcomes

D1 outcome

Examine Database: Skeletal Muscle Atrophy

Intervention	Grade	Evidence	Effect
Creatine	D	Participants: 29	No effect
Ephedrine	C	Participants: 10	Small Improvement
Medium-chain Triglycerides	C	Participants: 66	Small Improvement
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Creatine

No effect

Ephedrine

Small Improvement

Medium-chain Triglycerides

Small Improvement

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Skeletal Muscle Atrophy

Examine Database: Skeletal Muscle Atrophy

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