Examine Database: Preterm Birth Risk
| Intervention | Grade | Effect | Detail |
|---|---|---|---|
| Zinc | D | ||
| Vitamin D | A | ||
| Calcium | D | ||
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| Prenatal Vitamins | |||
| Vitamin C | |||
| Selenium | |||
Research FeedRead all studies
Does myo-inositol help prevent gestational diabetes?
In this systematic review of 5 randomized controlled trials in 893 pregnant women who were at high risk of gestational diabetes, myo-inositol appeared to reduce that risk, but the evidence is limited.
Low-dose and high-dose calcium with vitamin D improved pregnancy and neonatal outcomes
Zinc during pregnancy: Beneficial for the baby?
Vaping during pregnancy may be no safer than smoking
Cannabis use during pregnancy: What it means for the baby’s health
Examine Database References
- Vitamin C - Hauth JC, Clifton RG, Roberts JM, Spong CY, Myatt L, Leveno KJ, Pearson GD, Varner MW, Thorp JM Jr, Mercer BM, Peaceman AM, Ramin SM, Sciscione A, Harper M, Tolosa JE, Saade G, Sorokin Y, Anderson GB; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units Network (MFMU)Vitamin C and E supplementation to prevent spontaneous preterm birth: a randomized controlled trialObstet Gynecol.(2010 Sep)
- Zinc - Carducci B, Keats EC, Bhutta ZAZinc supplementation for improving pregnancy and infant outcome.Cochrane Database Syst Rev.(2021-Mar-16)
- Vitamin D - Moghib K, Ghanm TI, Abunamoos A, Rajabi M, Moawad SM, Mohsen A, Kasem S, Elsayed K, Sayed M, Dawoud AI, Salomon I, Elmaghreby A, Ismail M, Amer AEfficacy of vitamin D supplementation on the incidence of preeclampsia: a systematic review and meta-analysis.BMC Pregnancy Childbirth.(2024 Dec 23)
- Calcium - Buppasiri P, Lumbiganon P, Thinkhamrop J, Ngamjarus C, Laopaiboon M, Medley NCalcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes.Cochrane Database Syst Rev.(2015 Feb 25)
- Calcium - Mai-Lei Woo Kinshella, Shazmeen Omar, Kerri Scherbinsky, Marianne Vidler, Laura A Magee, Peter von Dadelszen, Sophie E Moore, Rajavel Elango, The Precise Conceptual Framework Working GroupEffects of Maternal Nutritional Supplements and Dietary Interventions on Placental Complications: An Umbrella Review, Meta-Analysis and Evidence MapNutrients.(2021 Jan 30)
- Calcium - Zhu Q, Yu Q, Liu M, Wei YEffectiveness of calcium supplementation in the prevention of gestational hypertension: A systematic review and meta-analysis of randomised controlled trials.Pregnancy Hypertens.(2024 Dec)
- Prenatal Vitamins - Dewey KG, Wessells KR, Arnold CD, Adu-Afarwuah S, Arnold BF, Ashorn P, Ashorn U, Garcés A, Huybregts L, Krebs NF, Lartey A, Leroy JL, Maleta K, Matias SL, Moore SE, Mridha MK, Okronipa H, Stewart CPEffects of prenatal small-quantity lipid-based nutrient supplements on pregnancy, birth, and infant outcomes: a systematic review and meta-analysis of individual participant data from randomized controlled trials in low- and middle-income countries.Am J Clin Nutr.(2024 Aug 16)
- Selenium - McDougall AR, Dore G, Aboud L, Makama M, Nguyen PY, Mills K, Sanderson B, Hastie R, Ammerdorffer A, Vogel JPThe effect of selenium supplementation in pregnant women on maternal, fetal, and newborn outcomes: a systematic review and meta-analysis.Am J Obstet Gynecol MFM.(2023-Nov)
- Vitamin C - Pereira AGA, Molino GOG, Santos ACFF, Dias MMF, Pimenta NDS, da Silva PHCMEfficacy of vitamin C supplementation during pregnancy in the prevention of preterm birth: a systematic review and meta-analysis.Rev Bras Ginecol Obstet.(2025)