Bovine lactoferrin for preventing respiratory tract infection symptoms Original paper

In this randomized controlled trial, adults who took a bovine lactoferrin supplement reported fewer respiratory tract infection symptoms than adults who took a placebo.

This Study Summary was published on November 30, 2023.

Quick Summary

In this randomized controlled trial, adults who took a bovine lactoferrin supplement reported fewer respiratory tract infection symptoms than adults who took a placebo.

What was studied?

The effect of supplementation with bovine lactoferrin on reported respiratory symptoms and systemic symptoms (primary outcomes).

The respiratory symptoms were throat discomfort, hoarseness, chest congestion, sneezing, runny nose, and plugged nose. The systemic symptoms were feeling feverish or unwell. All symptoms were scored on an 8-point Likert scale from 0 (no symptom) to 7 (severe symptom). The total scores of respiratory and systemic symptoms were calculated by summing the scores of individual symptoms.

The secondary outcomes were the expression of human leukocyte antigen-DR (HLA-DR) and cluster of differentiation 86 (CD86) on plasmacytoid dendritic cells (pDCs); these were assessed as markers of immune function.

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Who was studied?

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How was it studied?

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What were the results?

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Anything else I need to know?

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This Study Summary was published on November 30, 2023.