The participants were assigned to 1 of 4 groups:

Curcumin (80 milligrams of nanomicelle curcumin daily)
Curcumin + exercise (curcumin + 4 times per week of HIIT)
Placebo
Placebo + exercise

Compared to the placebo, all the active interventions (curcumin, curcumin plus exercise, and placebo plus exercise) increased (improved) irisin levels and improved blood lipids (total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides). It’s unclear whether the researchers compared the active interventions to one another.

Curcumin and/or HIIT may improve blood lipids in women with obesity Original paper