Twelve to 27 grams of Xiangshao granules or standard care were given for 8 to 12 weeks. Standard care consisted of hormone therapy, Xiaoyao pills, or a placebo.

Compared to standard care, Xiangshao granules had the following effects:

Increased the total effective rate (a primary outcome; a subjective measure of clinical success) by 178% (11 studies)
Improved menopausal symptom scores (a primary outcome) by a small amount (−1.23 on the Kupperman Index; 3 studies)
Improved estrogen, luteinizing hormone, and follicle-stimulating hormone with large effect sizes (4–9 studies)
Improved depression and anxiety scores by a small amount (2.5–2.8 on the Hamilton Anxiety and Depression Rating Scales; 3 studies each)
Did not increase the risk of adverse effects

Eleven studies had a moderate risk of bias, and 2 studies had a low risk of bias.

Can Xiangshao granules improve menopausal symptoms and hormone levels? Original paper