The closest possible recommended dose is based on rat studies where oral administration showed benefit, as most studies administer the supplement via injection. The oral dose that was effective in rats, 10 μg/kg, is estimated to be equivalent to 1.6 μg/kg, or:

• 110 μg for a 150lb person
• 145 μg for a 200lb person
• 180 μg for a 250lb person

There are currently no human pharmacokinetic studies to assess species differences.